SCHEMBL459121

SCHEMBL459121

Cc1ccc(O)cc1NCCO

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.67
TSHR P16473 1/20 0.67
RECQL P46063 1/20 0.67
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
GLA P06280 2/20 0.53
HPGD P15428 1/20 0.53
BRD4 O60885 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAP2K7 O14733 1/20 0.40
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
GUCY1A1 Q02108 1/20 0.39
GUCY1B1 Q02153 1/20 0.39
RIPK2 O43353 1/20 0.39
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3329752 0.92 CYP3A4 (0.57) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL6515933 0.85 KDM4E (0.53) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL21635494 0.85 CYP3A4 (0.72) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL11474259 0.82 GUCY1A1 (0.54) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL3266441 0.81 ALDH1A1 (0.61) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL126869 0.80 TSHR (1.00) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL9464298 0.79 TSHR (0.44) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL9741234 0.79 CYP3A4 (0.59) CYP3A4TSHRRECQLALDH1A1KDM4E
SCHEMBL2398365 0.79 CYP3A4 (0.64) CYP3A4TSHRRECQLALDH1A1KDM4E
Potassium SCHEMBL30495501 0.78 TSHR (0.96) CYP3A4TSHRRECQLALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105534785-B A kind of colouring compositions containing natural plant composition 肇庆迪彩日化科技有限公司 2018-11-02 CN claimed
EP-3393431-A1 COMPOSITION FOR DYEING THE HAIR, COMPRISING AN OXIDATION BASE, A 2-AMINO-5-ETHYLPHENOL COUPLER AND A FATTY SUBSTANCE L'OREAL (FR) 2018-10-31 EP claimed
WO-2017108841-A1 COMPOSITION FOR DYEING THE HAIR, COMPRISING AN OXIDATION BASE, A 2-AMINO-5-ETHYLPHENOL COUPLER AND A FATTY SUBSTANCE L'OREAL (FR) 2017-06-29 WO claimed
WO-1994004125-A1 HAIR DYE PREPARATIONS AND ASSOCIATED METHODS REVLON CONSUMER PRODUCTS CORPORATION (US) 1994-03-03 WO claimed
CN-103379894-B Comprise 1-hexyl/heptyl-4,5-diamino-pyrazole and 1,3-phenylenediamine and the oxidative dye compositions of derivant thereof 宝洁公司 2016-11-02 CN disclosed
EP-2370398-B1 Mixture of amides and cosmetic compositions comprising said mixture KAO CORP SA (ES) 2012-10-17 EP disclosed
US-8246697-B2 Mixture of amides and cosmetic compositions comprising said mixture KAO CORPORATION S.A. (ES) 2012-08-21 US disclosed
WO-2012032673-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2012-03-15 WO disclosed
US-20120005843-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE Kao Corporation S.A, (ES) 2012-01-12 US disclosed
EP-2370398-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE KAO CORPORATION, S.A. (ES) 2011-10-05 EP disclosed
EP-1714677-B1 Long chain fatty acid dimethylaminopropylamide as levelling agent for dyeing kerationous fibres KAO CORP SA (ES) 2010-07-14 EP disclosed
WO-2010072810-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE KAO CORPORATION, S.A. (ES) 2010-07-01 WO disclosed
EP-0910330-A4 HAIR DYE COMPOSITIONS AND PROCESS REVLON CONSUMER PROD CORP (US) 2001-03-21 EP disclosed
EP-0910330-A1 HAIR DYE COMPOSITIONS AND PROCESS Revlon Consumer Products Corporation (US) 1999-04-28 EP disclosed
WO-1998041186-A1 HAIR DYE COMPOSITIONS AND PROCESS REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-09-24 WO disclosed
EP-0633915-B1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1998-02-04 EP disclosed
US-5637354-A USING OXIDATIVE FIBER REACTIVE DYE SEGALLA GABRIELE (IT) 1997-06-10 US disclosed
EP-0633915-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA, Gabriele (IT) 1995-01-18 EP disclosed
WO-1994004125-A1 HAIR DYE PREPARATIONS AND ASSOCIATED METHODS REVLON CONSUMER PRODUCTS CORPORATION (US) 1994-03-03 WO disclosed
WO-1993020160-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120005843-A1 MIXTURE OF AMIDES AND COSMETIC COMPOSITIONS COMPRISING SAID MIXTURE H1-0, H1-3, H1-4 CYP3A4 530/4885TSHR 905/4885RECQL 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.