Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459121 | 0.92 | CYP3A4 (0.67) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL3336768 | 0.83 | TSHR (0.83) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| SCHEMBL25396737 | 0.81 | CYP3A4 (0.54) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| SCHEMBL2743946 | 0.81 | CYP3A4 (0.54) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| SCHEMBL11758466 | 0.81 | BRD4 (0.40) | CYP3A4RECQLTSHRALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL28861184 | 0.78 | MAPT (0.62) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL6515933 | 0.78 | KDM4E (0.53) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| SCHEMBL21635494 | 0.78 | CYP3A4 (0.72) | CYP3A4RECQLTSHRALDH1A1HPGD | |
| SCHEMBL11474259 | 0.75 | GUCY1A1 (0.54) | CYP3A4RECQLTSHRALDH1A1KDM4E | |
| SCHEMBL2398365 | 0.75 | CYP3A4 (0.64) | CYP3A4RECQLTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099332-A1 | MULTISTEP HAIR COLOR REVITALIZING KIT AND ASSOCIATED METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2008-08-21 | — | — | WO | claimed |
| US-20080189876-A1 | Multistep hair color revitalizing kit and associated methods | PROCTER & GAMBLE COMPANY, THE | 2008-08-14 | — | — | US | claimed |
| US-20100119561-A1 | Compositions Having a Performance Indicator | AMCOL INTERNATIONAL CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2008099332-A1 | MULTISTEP HAIR COLOR REVITALIZING KIT AND ASSOCIATED METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2008-08-21 | — | — | WO | disclosed |
| US-20080189876-A1 | Multistep hair color revitalizing kit and associated methods | PROCTER & GAMBLE COMPANY, THE | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119561-A1 | Compositions Having a Performance Indicator | STRA6, EXOSC5, CD63 | CYP3A4 1317/4885RECQL 316/4885TSHR 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.