Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146402 | 1.00 | KMT2A (0.45) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL146403 | 1.00 | KMT2A (0.45) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL146363 | 0.88 | KMT2A (0.48) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL1721452 | 0.88 | KMT2A (0.48) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL146364 | 0.88 | KMT2A (0.48) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 | |
| SCHEMBL1721155 | 0.87 | SIGMAR1 (0.43) | KMT2AL3MBTL1MAOBMAOADRD2 | |
| SCHEMBL1721160 | 0.87 | SIGMAR1 (0.43) | KMT2AL3MBTL1MAOBMAOADRD2 | |
| SCHEMBL3931356 | 0.82 | SIGMAR1 (0.41) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL3931359 | 0.82 | SIGMAR1 (0.41) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL7496942 | 0.81 | KMT2A (0.52) | KMT2AL3MBTL1KCNA3NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |