Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955316 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL2963930 | 0.83 | MEN1 (0.57) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL2954151 | 0.77 | SSTR5 (0.61) | ALDH1A1MCHR1 | |
| SCHEMBL2957960 | 0.77 | SSTR5 (0.61) | MCHR1 | |
| SCHEMBL2470064 | 0.75 | MEN1 (0.84) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL89655 | 0.74 | MEN1 (0.68) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL89358 | 0.74 | MEN1 (0.68) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL2958163 | 0.73 | SSTR5 (0.65) | MCHR1LMNA | |
| SCHEMBL2086693 | 0.73 | MEN1 (0.66) | ALDH1A1MCHR1POLBMEN1KMT2A | |
| SCHEMBL2960162 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MCHR1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |