Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464006 | 1.00 | SORD (0.51) | SORDALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL28145714 | 0.89 | SORD (0.45) | SORDALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL9767811 | 0.86 | — | — | |
| SCHEMBL30775404 | 0.82 | SORD (0.56) | SORDALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL4453478 | 0.82 | SORD (0.56) | SORDALDH1A1SMN1; SMN2GSK3BLMNA | |
| SCHEMBL18768480 | 0.81 | SORD (0.46) | SORDCYP1A2CYP2C9CYP2C19PIK3CA | |
| SCHEMBL209842 | 0.80 | SORD (0.54) | SORDALDH1A1CYP1A2SMN1; SMN2GSK3B | |
| SCHEMBL29611181 | 0.80 | SORD (0.54) | SORDALDH1A1CYP1A2SMN1; SMN2GSK3B | |
| SCHEMBL209844 | 0.80 | SORD (0.54) | SORDALDH1A1CYP1A2SMN1; SMN2GSK3B | |
| SCHEMBL2103794 | 0.78 | SORD (0.53) | SORDLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117000066-A | Composite reverse osmosis membrane, preparation method thereof and application thereof in generator insulating paint wastewater treatment | 四川大学 | 2023-11-07 | — | — | CN | claimed |
| CN-104086562-B | The preparation of the heterocycle miazines compound containing virtue hydrazone structure and application | 江西科技师范大学 | 2016-09-07 | — | — | CN | claimed |
| CN-102643272-B | Novel thieno [3, 2-d] pyrimidine compound | UNIV SHENYANG PHARMACEUTICAL | 2015-03-11 | — | — | CN | claimed |
| CN-104086562-A | Preparation method and application of heterocyclopyrimidine compound containing aryl hydrazone structure | UNIV JIANGXI NORMAL SCI & TECH | 2014-10-08 | — | — | CN | claimed |
| EP-2064203-A1 | 2-BENZIMIDAZ0LYL-6-M0RPH0LIN0-4-PIPERIDIN-4-YLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2009-06-03 | — | — | EP | claimed |
| EP-2057147-A1 | PYRIMIDINE DERIVATIVES | Astra Zeneca AB (SE) | 2009-05-13 | — | — | EP | claimed |
| WO-2008032064-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2008032072-A1 | 2-BENZIMIDAZ0LYL-6-M0RPH0LIN0-4-PIPERIDIN-4-YLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2007066099-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | WO | claimed |
| WO-2007066103-A1 | PYRIMIDINE DERIVATIVES AS CLASS I PI3K INHIBITOR | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | WO | claimed |
| EP-1768978-A1 | 2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | AstraZeneca AB (SE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006005914-A1 | 2, 4, 6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2006-01-19 | — | — | WO | claimed |
| EP-4438734-A2 | REPROGRAMMING OF CELLS TO A NEW FATE | The Scripps Research Institute (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-3399026-B1 | REPROGRAMMING OF CELLS TO A NEW FATE | SCRIPPS RESEARCH INST (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-111918651-B | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117000066-A | Composite reverse osmosis membrane, preparation method thereof and application thereof in generator insulating paint wastewater treatment | 四川大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-1196685-C | Pyrimidine derivatives | ASTRAZENCA AB (SE) | 2005-04-13 | — | — | CN | disclosed |
| CN-1454210-A | Pyrimidine derivatives | ASTRAZENCA AB (SE) | 2003-11-05 | — | — | CN | disclosed |
| EP-0232025-A2 | Dihydropyridine anti-ischaemic and antihypertensive agents | Pfizer Limited (GB) | 1987-08-12 | — | — | EP | disclosed |
| US-4565864-A | INTERMEDIATES FOR BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1986-01-21 | — | — | US | disclosed |