Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.54 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209842 | 1.00 | SORD (0.54) | SORDCHKAMAPTALDH1A1LMNA | |
| SCHEMBL29611181 | 1.00 | SORD (0.54) | SORDCHKAMAPTALDH1A1LMNA | |
| SCHEMBL4453478 | 0.98 | SORD (0.56) | SORDCHKAMAPTALDH1A1LMNA | |
| SCHEMBL30775404 | 0.98 | SORD (0.56) | SORDCHKAMAPTALDH1A1LMNA | |
| SCHEMBL9767811 | 0.89 | — | — | |
| Imidazole SCHEMBL19693057 | 0.83 | SORD (0.48) | SORDCHKAMAPTALDH1A1LMNA | |
| SCHEMBL24742884 | 0.82 | SORD (0.50) | SORDALDH1A1TSHRGSK3BROCK2 | |
| SCHEMBL2224541 | 0.82 | SORD (0.53) | SORDGPR119DRD4ROCK1AKT1 | |
| SCHEMBL2103794 | 0.82 | SORD (0.53) | SORDGPR119DRD4ROCK1AKT1 | |
| SCHEMBL9558132 | 0.80 | SORD (0.55) | SORDALDH1A1TSHRGPR119GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960888-A | Preparation of 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-10-02 | — | — | US | claimed |
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | DONG-A ST CO., LTD. (KR) | 2025-03-04 | — | — | US | disclosed |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | disclosed |
| US-11858940-B2 | Selective modulators of mutant LRRK2 proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220010323-A1 | METHOD TO OBTAIN LOW TRITERPENE/TRITERPENOID-CONTAINING NATURAL RUBBER LATEX | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2022-01-13 | — | — | US | disclosed |
| EP-3877518-A1 | METHOD TO OBTAIN LOW TRITERPENE/TRITERPENOID-CONTAINING NATURAL RUBBER LATEX | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2021-09-15 | — | — | EP | disclosed |
| CN-112955545-A | Method for obtaining natural rubber latex with low triterpene/triterpenoid content | 弗劳恩霍夫应用研究促进协会 | 2021-06-11 | — | — | CN | disclosed |
| EP-3650542-A1 | METHOD TO OBTAIN LOW TRITERPENE/TRITERPENOID-CONTAINING NATURAL RUBBER LATEX | Fraunhofer Gesellschaft zur Förderung der Angewand (DE) | 2020-05-13 | — | — | EP | disclosed |
| CN-109731001-A | The newly new application of fine jade oligosaccharides and the composition containing new fine jade oligosaccharides | 蓝脑科技(厦门)有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109053742-A | New tricyclic compound | ABBVIE 公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20050020645-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1405852-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1049473-A1 | PYRIMIDIN 3-OXIDE COMPOUNDS SUITABLE FOR THE TREATMENT OF PATHOLOGIES OF THE SKELETAL MUSCLE, IN PARTICULAR FOR THE TREATMENT OF THE HYPOKALEMIC PARALYSIS | Paolini, Moreno (IT) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999036072-A1 | PYRIMIDIN 3-OXIDE COMPOUNDS SUITABLE FOR THE TREATMENT OF PATHOLOGIES OF THE SKELETAL MUSCLE, IN PARTICULAR FOR THE TREATMENT OF THE HYPOKALEMIC PARALYSIS | PAOLINI MORENO (IT) | 1999-07-22 | — | — | WO | disclosed |
| EP-0640599-B1 | 4-Aminopyrimidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5525604-A | USED IN PREVENTION OR TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |
| CN-1109055-A | 4-aminopyrimidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-09-27 | — | — | CN | disclosed |
| EP-0640599-A1 | 4-Aminopyrimidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-86102398-A | The preparation method of substituted benzimidazole derivative | — | 1986-11-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020645-A1 | Diamine derivatives | C9, C1S, C1R | SORD 2798/4885CHKA 4617/4885MAPT 4271/4885 |
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | EIF2AK4, GCN1, GCGR | SORD 3130/4885CHKA 3963/4885MAPT 2789/4885 |
| US-11858940-B2 | Selective modulators of mutant LRRK2 proteolysis and associated methods of use | LRRK2, ADRM1, CRBN | SORD 4280/4885CHKA 555/4885MAPT 673/4885 |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EIF2AK4, GCN1, GCGR | SORD 3130/4885CHKA 3963/4885MAPT 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.