Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728797 | 1.00 | — | — | |
| SCHEMBL8258119 | 1.00 | — | — | |
| SCHEMBL12196225 | 1.00 | — | — | |
| SCHEMBL19658189 | 0.97 | THRA (0.32) | ALDH1A1SMN1; SMN2NLRP3 | |
| SCHEMBL10659774 | 0.81 | — | — | |
| SCHEMBL17681982 | 0.79 | — | — | |
| SCHEMBL21957841 | 0.79 | — | — | |
| SCHEMBL10907748 | 0.79 | — | — | |
| SCHEMBL15172351 | 0.75 | CHRM2 (0.40) | — | |
| SCHEMBL17928477 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511477-A4 | HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETOEPOXIDE COMPOUNDS | ERRANT GENE THERAPEUTICS LLC (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-1511477-A1 | HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETOEPOXIDE COMPOUNDS | Errant Gene Therapeutics, LLC (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099272-A1 | HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETOEPOXIDE COMPOUNDS | ERRANT GENE THERAPEUTICS, LLC (US) | 2003-12-04 | — | — | WO | disclosed |