⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258119 | 1.00 | — | — | |
| SCHEMBL4591609 | 1.00 | ALDH1A1 (0.33) | — | |
| SCHEMBL12196225 | 1.00 | — | — | |
| SCHEMBL19658189 | 0.97 | THRA (0.32) | — | |
| SCHEMBL10659774 | 0.81 | — | — | |
| SCHEMBL17681982 | 0.79 | — | — | |
| SCHEMBL21957841 | 0.79 | — | — | |
| SCHEMBL10907748 | 0.79 | — | — | |
| SCHEMBL15172351 | 0.75 | CHRM2 (0.40) | — | |
| SCHEMBL17928477 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735442-A1 | IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS | Theranib Inc. (CA) | 2026-05-06 | — | — | EP | claimed |
| US-20250011322-A1 | MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A | THERANIB INC. (CA) | 2025-01-09 | — | — | US | claimed |
| CN-117659300-A | Quick-dispersion polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117659382-A | Acetyl-terminated polyether macromonomer and preparation method thereof, and concrete water reducer and preparation method thereof | 科之杰新材料集团有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117263863-A | Arylamine alkyl substituted imidazoles compound and its synthesis method and use | 吉首大学 | 2023-12-22 | — | — | CN | claimed |
| CN-107417535-B | A kind of one-pot synthesis method of highly selective (E)-beta-nitrostyrene derivative | 沅江华龙催化科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| EP-4735442-A1 | IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS | Theranib Inc. (CA) | 2026-05-06 | — | — | EP | disclosed |
| US-20250011322-A1 | MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A | THERANIB INC. (CA) | 2025-01-09 | — | — | US | disclosed |
| CN-117659300-A | Quick-dispersion polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117659382-A | Acetyl-terminated polyether macromonomer and preparation method thereof, and concrete water reducer and preparation method thereof | 科之杰新材料集团有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117263863-A | Arylamine alkyl substituted imidazoles compound and its synthesis method and use | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |
| US-20230271938-A1 | BENZIMIDAZOLES FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | CAPELLA THERAPEUTICS, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-6262278-B1 | REACTING WATER AND MIXTURE OF STEREOISOMERS OF CHIRAL CYCLIC SUBSTRATE IN THE PRESENCE OF NON-RACEMIC CHIRAL CATALYST TO PRODUCE BY KINETIC RESOLUTION STEREOISOMERICALLY ENRICHED CYCLIC SUBSTRATE OR STEREOISOMERICALLY ENRICHED HYDROLYZATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-07-17 | — | — | US | disclosed |
| EP-1104395-A1 | STEREOSELECTIVE RING OPENING REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009463-A1 | STEREOSELECTIVE RING OPENING REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-24 | — | — | WO | disclosed |
| CN-1163623-A | Graft-modified ethylene-vinyl acetate copolymer and resin composition thereof | KANEGAFUCHI CHEMICAL IND (JP) | 1997-10-29 | — | — | CN | disclosed |
| US-4006169-A | 1,1,1-TRICHLORO-3,4-EPOXY-2-BUTANONE OR 1,1,1-TRICHLORO-2,2-DIHYDROXY-3,4-EPOXYBUTANE | SMITHKLINE CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4006169-A | 1,1,1-TRICHLORO-3,4-EPOXY-2-BUTANONE OR 1,1,1-TRICHLORO-2,2-DIHYDROXY-3,4-EPOXYBUTANE | SMITHKLINE CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3957745-A | FLAVORING AND FRAGRANCE COMPOSITIONS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-05-18 | — | — | US | disclosed |