Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577590 | 0.88 | OPRD1 (0.57) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL5145212 | 0.88 | OPRD1 (0.57) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL4576061 | 0.84 | OPRD1 (0.58) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL6936263 | 0.84 | OPRD1 (0.57) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL6936260 | 0.84 | OPRD1 (0.57) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL4575844 | 0.84 | OPRD1 (0.59) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL4575681 | 0.84 | OPRD1 (0.59) | OPRD1OPRM1CYP3A4CYP1A2OPRK1 | |
| SCHEMBL8069321 | 0.84 | OPRD1 (0.53) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL8069179 | 0.84 | OPRD1 (0.53) | OPRD1OPRM1MEN1KMT2ACYP3A4 | |
| SCHEMBL7093363 | 0.83 | CYP3A4 (0.61) | OPRD1OPRM1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469850-A4 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1469850-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | Ardent Pharmaceuticals, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003057223-A9 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS INC (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2003057223-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | disclosed |