Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572401 | 0.80 | EPHX2 (0.56) | EPHX2MEN1KMT2APARP1EPHX1 | |
| SCHEMBL19639670 | 0.78 | L3MBTL1 (0.47) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29268419 | 0.77 | NPC1 (0.61) | EPHX2MEN1KMT2AEPHX1MAPT | |
| SCHEMBL8366262 | 0.76 | KMT2A (0.70) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28579659 | 0.74 | USP30 (0.52) | MEN1KMT2AALDH1A1KDM4ECRHBP | |
| SCHEMBL4852930 | 0.74 | USP30 (0.58) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23534299 | 0.74 | L3MBTL1 (0.49) | MEN1KMT2AALDH1A1KDM4ECRHBP | |
| SCHEMBL2953693 | 0.73 | SMYD3 (0.58) | EPHX2MEN1KMT2AEPHX1MAPT | |
| SCHEMBL22083658 | 0.73 | USP30 (0.56) | MEN1KMT2AALDH1A1KDM4EPARP1 | |
| SCHEMBL22160845 | 0.73 | SMYD3 (0.58) | EPHX2KMT2AALDH1A1PARP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |