Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522040 | 0.88 | F10 (0.43) | F10SYKKLKB1MAPK1 | |
| SCHEMBL1030894 | 0.82 | F10 (0.47) | F10SYKKLKB1 | |
| Hydrochloric Acid SCHEMBL4999282 | 0.81 | F10 (0.47) | F10SYKKLKB1 | |
| SCHEMBL13907449 | 0.79 | KMT2A (0.53) | F10MAPK1 | |
| SCHEMBL4495700 | 0.78 | F10 (0.40) | F10SYKMAPK1 | |
| SCHEMBL1029269 | 0.78 | THRB (0.44) | F10KLKB1 | |
| SCHEMBL4238560 | 0.77 | F10 (0.58) | F10 | |
| Trifluoroacetic Acid SCHEMBL3448168 | 0.75 | F10 (0.45) | F10KLKB1MAPK1 | |
| SCHEMBL4056635 | 0.75 | F10 (0.53) | F10 | |
| SCHEMBL8307362 | 0.75 | F10 (0.47) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877404-A2 | NOVEL CYCLIC AMINES | F. Hoffmann-Roche AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |