Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688563 | 0.87 | MYC (0.54) | F10HSD17B10KDM4EALDH1A1HTR7 | |
| SCHEMBL2640132 | 0.82 | F10 (0.59) | F10HSD17B10KDM4EBRD4ALDH1A1 | |
| SCHEMBL1828212 | 0.80 | PARP1 (0.46) | HSD17B10KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL18755235 | 0.78 | MAPT (0.47) | KDM4EALDH1A1BRPF1SMN1; SMN2ALOX15 | |
| SCHEMBL8306577 | 0.78 | NPSR1 (0.47) | HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4238560 | 0.76 | F10 (0.58) | F10HSD17B10PARP1PARP10 | |
| SCHEMBL4688126 | 0.75 | F10 (0.61) | F10 | |
| SCHEMBL4687631 | 0.75 | F10 (0.58) | F10 | |
| SCHEMBL31637513 | 0.75 | HCAR1 (0.46) | F10HSD17B10KDM4EBRD4ALDH1A1 | |
| SCHEMBL4591950 | 0.75 | F10 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |