Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730133 | 0.80 | KEAP1 (0.51) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL4592215 | 0.80 | CYP2A6 (0.53) | CYP2A6CA2MAPTSMN1; SMN2MTNR1A | |
| SCHEMBL6202916 | 0.79 | KEAP1 (0.75) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL27615372 | 0.76 | CYP2A6 (0.65) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL5469050 | 0.76 | CYP2A6 (0.65) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL4324624 | 0.76 | CYP2A6 (0.75) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL29244282 | 0.75 | IDO1 (0.50) | EPHX1 | |
| SCHEMBL13995271 | 0.75 | KEAP1 (0.69) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL29679218 | 0.75 | KEAP1 (0.61) | KEAP1NFE2L2CYP2A6CA2EPHX1 | |
| SCHEMBL4323833 | 0.74 | KEAP1 (0.63) | KEAP1NFE2L2CYP2A6CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904443-A1 | NEW BENZOHETEROCYCLYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006734-A1 | NEW BENZOHETEROCYCLYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-01-18 | — | — | WO | disclosed |