Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 2/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591784 | 0.92 | MEN1 (0.51) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4591345 | 0.91 | REN (0.46) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4591707 | 0.89 | POLB (0.44) | MEN1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL4591677 | 0.87 | POLB (0.42) | MEN1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL4591877 | 0.83 | REN (0.45) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4591603 | 0.83 | MEN1 (0.53) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4590753 | 0.82 | REN (0.49) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4630166 | 0.81 | POLB (0.43) | MEN1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL4591455 | 0.80 | TACR1 (0.37) | MEN1HPGDKMT2ASMN1; SMN2REN | |
| SCHEMBL4591790 | 0.80 | SLC6A4 (0.36) | MEN1HPGDKMT2ASMN1; SMN2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |