Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTPS1 | Q14703 | 9/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591469 | 0.88 | HTR2A (0.43) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4591350 | 0.88 | REN (0.48) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4610673 | 0.83 | MBTPS1 (0.37) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4591502 | 0.83 | HDAC3 (0.40) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4591595 | 0.81 | HDAC3 (0.39) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4592438 | 0.81 | POLB (0.43) | SLC6A4SLC6A2SLC6A3KCNH2THRB | |
| SCHEMBL4590911 | 0.80 | TACR1 (0.36) | MBTPS1F10PLAUSLC6A4SLC6A2 | |
| SCHEMBL4591405 | 0.77 | POLB (0.43) | SLC6A4SLC6A2SLC6A3KCNH2THRB | |
| SCHEMBL4590615 | 0.76 | POLB (0.41) | SLC6A4SLC6A2SLC6A3KCNH2THRB | |
| SCHEMBL4591677 | 0.76 | POLB (0.42) | SLC6A4SLC6A2SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |