Methacrylic Acid

Methacrylic Acid

SCHEMBL2641341

C=C(C)C(=O)O.C=C(C)C(=O)O.C=CCOC(=O)C=C.OCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
ALDH1A1 P00352 6/20 0.39
TP53 P04637 4/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 3/20 0.39
MAPK1 P28482 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 2/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
HSD17B10 Q99714 2/20 0.38
THRB P10828 2/20 0.33
APP P05067 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL30200325 0.97 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL316282 0.94 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL14362184 0.93 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL459213 0.93 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
1,6-Hexanediol SCHEMBL8212859 0.92 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL8664308 0.91 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL8516311 0.91 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL1173477 0.88 MAPT (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL6275938 0.88 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Ethyl Ester SCHEMBL3278000 0.88 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4791732-B2 2011-10-12 JP claimed
EP-1583803-B1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS BASF SE (DE) 2010-07-28 EP claimed
EP-1583803-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 2005-10-12 EP claimed
US-6867301-B2 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-15 US claimed
WO-2004063284-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-29 WO claimed
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed
US-4804531-A Cosmetic screening composition containing a UV screen in combination with a polymer obtained by block polymerization in emulsion and its use for the protection of the human epidermis against ultraviolet radiations L'OREAL (FR) 1989-02-14 US claimed
EP-1583803-B1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS BASF SE (DE) 2010-07-28 EP disclosed
EP-1583803-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 2005-10-12 EP disclosed
US-6867301-B2 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-15 US disclosed
WO-2004063284-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-29 WO disclosed
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US disclosed
US-6726758-B2 CARBON BLACK, A MAGENTA PIGMENT, AND A CYAN PIGMENT AS COLORANTS, AND THE PLURALITY OF BLACK INK COMPOSITIONS ARE DIFFERENT FROM EACH OTHER IN CONTENT OF CARBON BLACK, AND THE CONTENT OF THE MAGENTA PIGMENT SEIKO EPSON CORPORATION (JP) 2004-04-27 US disclosed
US-20030056687-A1 Black ink set and recording method using the same SEIKO EPSON CORPORATION 2003-03-27 US disclosed
US-6440203-B2 WATER SOLUBILITY SEIKO EPSON CORPORATION (JP) 2002-08-27 US disclosed
US-20010035110-A1 Ink composition capable of realizing images possessing excellent color development and fixation SEIKO EPSON CORPORATION 2001-11-01 US disclosed
EP-1114851-A1 Ink composition capable of realizing images possessing excellent color development and fixation SEIKO EPSON CORPORATION (JP) 2001-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments NDUFA6, NDUFS6, NDUFA3 TSHR 4164/4885ALDH1A1 88/4885TP53 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.