SCHEMBL4592398

SCHEMBL4592398

CCOC(=O)/C=C/c1ccc(OC)cc1OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.68
ALDH1A1 P00352 6/20 0.68
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
LY96 Q9Y6Y9 1/20 0.63
TNFRSF1A P19438 1/20 0.62
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
CYP1A1 P04798 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP1B1 Q16678 1/20 0.58
MAPK1 P28482 2/20 0.58
BACE1 P56817 1/20 0.57
ESR1 P03372 1/20 0.57
HPGD P15428 3/20 0.56
LMNA P02545 2/20 0.56
KDM4E B2RXH2 3/20 0.56
TXNRD1 Q16881 1/20 0.56
TXNRD3 Q86VQ6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4592405 1.00 MAPT (0.68) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL7205018 0.92 HDAC8 (0.58) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL10669860 0.92 MAPT (0.61) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL25288435 0.92 HDAC8 (0.58) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL10669864 0.92 MAPT (0.61) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL28214362 0.90 FDPS (0.67) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL9469851 0.89 CYP1A1 (0.57) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL9469853 0.89 CYP1A1 (0.57) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL22867612 0.87 MAOB (0.57) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL29581080 0.87 MAOB (0.57) MAPTALDH1A1MEN1KMT2ALY96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021215943-A1 XANTHONE DERIVATIVES, UV PROTECTIVE COMPOSITION CONCENTRATE, METHOD OF PREPARATION OF UV PROTECTIVE COMPOSITION CONCENTRATE, USE OF UV PROTECTIVE COMPOSITION CONCENTRATE AND COSMETIC UV PROTECTIVE PRODUCT UNIWERSYTET JAGIELLONSKI (PL) 2021-10-28 WO disclosed
EP-1896169-A1 METHOD OF REDUCING THE LEVEL OF NITROGEN OXIDES IN A MEDIUM BY ABSORPTION WITH RESORCIN[4]ARENES British American Tobacco Italia S.p.A. (IT) 2008-03-12 EP disclosed
EP-1738821-A1 Method of reducing the level of nitrogen oxides in a medium by absorption with resorcin¬4|arenes British American Tobacco Italia S.p.A. (IT) 2007-01-03 EP disclosed
EP-1738821-A1 Method of reducing the level of nitrogen oxides in a medium by absorption with resorcin¬4|arenes British American Tobacco Italia S.p.A. (IT) 2007-01-03 EP disclosed
WO-2006136950-A1 METHOD BRITISH AMERICAN TOBACCO ITALIA S.P.A. (IT) 2006-12-28 WO disclosed
US-5124478-A ACID-LABILE ANCHOR GROUPS FOR THE SYNTHESIS OF PEPTIDE AMIDES BY A SOLID-PHASE METHOD HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-23 US disclosed