Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493372 | 0.89 | POLB (0.53) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3491512 | 0.86 | POLB (0.48) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3494438 | 0.82 | POLB (0.52) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4520199 | 0.77 | KMT2A (0.63) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3492282 | 0.75 | ERCC1 (0.57) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3495342 | 0.74 | POLB (0.50) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3492250 | 0.73 | ALDH1A1 (0.56) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3492238 | 0.72 | BCAT2 (0.52) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3494030 | 0.72 | TSHR (0.53) | POLBTDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3494115 | 0.72 | POLB (0.47) | POLBTDP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908765-A1 | THIENOPYRIMIDINE DERIVATIVE | ASKA Pharmaceutical Co., Ltd. (JP) | 2008-04-09 | — | — | EP | disclosed |