Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251220 | 0.94 | TDP1 (0.48) | TDP1ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL272368 | 0.94 | TDP1 (0.48) | TDP1ALDH1A1NPC1RAB9APOLB | |
| Water SCHEMBL27475250 | 0.91 | TDP1 (0.46) | TDP1ALDH1A1NPC1RAB9APOLB | |
| Ammonia Solution, Strong SCHEMBL2333633 | 0.91 | TDP1 (0.46) | TDP1ALDH1A1NPC1RAB9APOLB | |
| Ammonia Solution, Strong SCHEMBL10952443 | 0.89 | TDP1 (0.44) | TDP1ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL5009477 | 0.88 | TDP1 (0.40) | TDP1TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL23924264 | 0.86 | SLC6A2 (0.47) | TDP1ALDH1A1NPC1RAB9APOLB | |
| Acetic Acid SCHEMBL27497151 | 0.86 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL22589949 | 0.82 | HRH3 (0.49) | ALDH1A1CA2 | |
| SCHEMBL28249454 | 0.82 | TDP1 (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900800-A2 | 4-phenyl-pentan-2-ol as odorous and aromatic substance | Symrise GmbH & Co. KG (DE) | 2008-03-19 | — | — | EP | disclosed |
| US-20080064625-A1 | 4-Phenylpentan-2-ol as a fragrance and flavouring | SYMRISE GMBH & CO. KG (DE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064625-A1 | 4-Phenylpentan-2-ol as a fragrance and flavouring | PNN, P4HA1, DPM1 | TDP1 3073/4885TP53 1610/4885TSHR 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.