Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | FPR2 | P25090 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47376 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2FPR2KAT2BALDH1A1 | |
| SCHEMBL2627811 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2FPR2CYP2D6TSHRCYP2C19 | |
| SCHEMBL2627813 | 0.83 | SMN1; SMN2 (0.97) | SMN1; SMN2FPR2MAPTCYP2D6TSHR | |
| SCHEMBL4395997 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2FPR2CYP2D6TSHRCYP2C19 | |
| SCHEMBL45931 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2FPR2CYP2D6TSHRCYP2C19 | |
| SCHEMBL27699241 | 0.80 | KDM4E (0.55) | SMN1; SMN2FPR2MAPTCYP2D6CYP2C19 | |
| SCHEMBL2962697 | 0.80 | KMT2A (0.57) | SMN1; SMN2TSHRKMT2AKAT2BALDH1A1 | |
| SCHEMBL16364921 | 0.78 | TLR8 (0.50) | SMN1; SMN2FPR2MAPTTSHRKMT2A | |
| SCHEMBL9726075 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2FPR2MAPTTSHRKMT2A | |
| SCHEMBL2230908 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2FPR2GAACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304516-B | Method for preparing beta-aminoketone, ester and nitrile amide derivatives | UNIV TAIZHOU | 2015-02-11 | — | — | CN | disclosed |
| CN-103304516-A | Method for preparing beta-aminoketone, ester and nitrile amide derivatives | UNIV TAIZHOU | 2013-09-18 | — | — | CN | disclosed |
| US-8383721-B2 | Polymerizable ionic liquid compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| CN-101723771-B | Novel method for preparing beta-aminoketone, ester, nitrile and amide derivatives through catalysis of functional ionic liquid | ZHEJIANG MED XINCHANG PHARM | 2012-12-05 | — | — | CN | disclosed |
| US-20110288227-A1 | POLYMERIZABLE IONIC LIQUID COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-11-24 | — | — | US | disclosed |
| CN-101723771-A | Novel method for preparing beta-aminoketone, ester, nitrile and amide derivatives through catalysis of functional ionic liquid | UNIV ZHEJIANG | 2010-06-09 | — | — | CN | disclosed |