SCHEMBL47376

SCHEMBL47376

CCOC(=O)CCn1ccnc1C(C)C

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.65
FPR2 P25090 8/20 0.59
LMNA P02545 1/20 0.43
TNF P01375 5/20 0.43
CREBBP Q92793 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KAT2B Q92831 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45929 0.85 SMN1; SMN2 (0.68) SMN1; SMN2FPR2ALDH1A1KAT2B
SCHEMBL2970107 0.82 ALDH1A1 (0.53) SMN1; SMN2FPR2LMNATNFCREBBP
SCHEMBL2627811 0.82 SMN1; SMN2 (0.63) SMN1; SMN2FPR2
SCHEMBL45931 0.81 SMN1; SMN2 (0.70) SMN1; SMN2FPR2
SCHEMBL28422751 0.81 FPR2 (0.48) SMN1; SMN2FPR2LMNATNFCREBBP
SCHEMBL2627813 0.80 SMN1; SMN2 (0.97) SMN1; SMN2FPR2
SCHEMBL2230908 0.80 SMN1; SMN2 (0.57) SMN1; SMN2FPR2
SCHEMBL47378 0.79 FPR2 (0.47) FPR2LMNATNFCREBBPALDH1A1
SCHEMBL4395997 0.79 SMN1; SMN2 (0.72) SMN1; SMN2FPR2LMNA
SCHEMBL21167189 0.77 FPR2 (0.46) FPR2LMNATNFCREBBPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571908-B1 POLYMERIZABLE IONIC LIQUID COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2017-04-26 EP disclosed
US-8383721-B2 Polymerizable ionic liquid compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-26 US disclosed
US-8383721-B2 Polymerizable ionic liquid compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-26 US disclosed
US-20110288227-A1 POLYMERIZABLE IONIC LIQUID COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2011-11-24 US disclosed