Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852753 | 0.88 | KDM4E (0.55) | NFE2L2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14501345 | 0.88 | NFE2L2 (0.54) | NFE2L2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14143273 | 0.88 | NFE2L2 (0.54) | NFE2L2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1884884 | 0.87 | ABCG2 (0.62) | NFE2L2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1884886 | 0.87 | ABCG2 (0.62) | NFE2L2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL4775241 | 0.87 | KDM4E (0.67) | NFE2L2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15188 | 0.87 | KDM4E (0.67) | NFE2L2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31506312 | 0.87 | KDM4E (0.67) | NFE2L2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13957562 | 0.87 | KDM4E (0.67) | NFE2L2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7438631 | 0.85 | NFE2L2 (0.77) | NFE2L2L3MBTL1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896169-A1 | METHOD OF REDUCING THE LEVEL OF NITROGEN OXIDES IN A MEDIUM BY ABSORPTION WITH RESORCIN[4]ARENES | British American Tobacco Italia S.p.A. (IT) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006136950-A1 | METHOD | BRITISH AMERICAN TOBACCO ITALIA S.P.A. (IT) | 2006-12-28 | — | — | WO | disclosed |