Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL4593156 | 0.79 | SMN1; SMN2 (0.42) | LMNASLC6A6CYP2C19BLMALDH1A1 | |
| SCHEMBL220468 | 0.77 | F10 (0.48) | F10ALDH1A1ACKR3HRH3CYP2D6 | |
| SCHEMBL221799 | 0.77 | KDM1A (0.42) | ALDH1A1ACKR3HRH3CYP2D6KDM1A | |
| Hydrochloric Acid SCHEMBL2104255 | 0.75 | KDM1A (0.41) | ALDH1A1ACKR3HRH3CYP2D6KDM1A | |
| SCHEMBL4592504 | 0.74 | MAOB (0.49) | ALDH1A1KDM1AMAPT | |
| Taurine SCHEMBL4592404 | 0.73 | CYP2C19 (0.36) | CYP2C19F10ALDH1A1HRH3KDM1A | |
| SCHEMBL222294 | 0.72 | F10 (0.46) | F10ALDH1A1ACKR3HRH3CYP2D6 | |
| Fumaric Acid SCHEMBL3873534 | 0.71 | F10 (0.47) | F10ALDH1A1ACKR3HRH3CYP2D6 | |
| SCHEMBL29346783 | 0.70 | KDM1A (0.38) | ALDH1A1HRH3CYP2D6KDM1AMAPT | |
| SCHEMBL19623362 | 0.70 | KDM1A (0.38) | ALDH1A1HRH3CYP2D6KDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |