Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221764 | 0.86 | HRH3 (0.43) | CYP2C19HRH3MC4RKDM1AMAOB | |
| Taurine SCHEMBL4592400 | 0.81 | F10 (0.39) | HRH3F10ALDH1A1 | |
| Taurine SCHEMBL4593157 | 0.73 | LMNA (0.41) | CYP2C19HRH3F10KDM1AALDH1A1 | |
| SCHEMBL222300 | 0.73 | HDAC6 (0.34) | CYP2C19HRH3CYP1A2CYP2C9 | |
| SCHEMBL4592402 | 0.71 | HRH3 (0.34) | HRH3F10 | |
| SCHEMBL3480924 | 0.70 | KDM1A (0.53) | CYP2C19KDM1AMAOBALDH1A1 | |
| SCHEMBL8155144 | 0.68 | TSHR (0.47) | CYP2C19KDM1AMAOBMCHR1ALDH1A1 | |
| SCHEMBL14492292 | 0.67 | KDM1A (0.47) | CYP2C19KDM1AMAOBALDH1A1MTTP | |
| SCHEMBL14506765 | 0.67 | KDM1A (0.47) | CYP2C19KDM1AMAOBALDH1A1MTTP | |
| Taurine SCHEMBL4593156 | 0.66 | SMN1; SMN2 (0.42) | CYP2C19HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |