Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592501 | 0.83 | MAOB (0.48) | MAOBACHEALDH1A1KMT2AMAPT | |
| SCHEMBL222333 | 0.83 | MAOB (0.52) | MAOBACHEALDH1A1DRD2KDM1A | |
| SCHEMBL4592502 | 0.76 | MAOB (0.50) | MAOBACHEALDH1A1MAPT | |
| SCHEMBL496740 | 0.76 | GLS (0.53) | ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL219546 | 0.75 | MAOB (0.51) | MAOBACHEDRD2HPGD | |
| Potassium SCHEMBL6284198 | 0.75 | GLS (0.52) | ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6284185 | 0.75 | GLS (0.52) | ALDH1A1KMT2AMAPTHPGD | |
| Taurine SCHEMBL4593157 | 0.74 | LMNA (0.41) | ALDH1A1MAPTKDM1A | |
| SCHEMBL221260 | 0.70 | MAOB (0.46) | MAOBACHEDRD2 | |
| SCHEMBL918303 | 0.68 | TDP1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |