SCHEMBL4593276

SCHEMBL4593276

CC(c1ccc(O)cc1)C(Cl)(Cl)Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.60
ESR2 Q92731 9/20 0.60
PDCD1 Q15116 1/20 0.54
CD274 Q9NZQ7 1/20 0.54
LMNA P02545 3/20 0.43
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
ALOX15 P16050 2/20 0.43
CYP2D6 P10635 2/20 0.43
SLC6A2 P23975 2/20 0.43
ADRA1A P35348 2/20 0.43
OPRM1 P35372 2/20 0.43
SLC6A3 Q01959 2/20 0.43
CYP2C9 P11712 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 1/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
AR P10275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541722 0.79 ESR1 (0.47) ESR1ESR2PDCD1CD274LMNA
SCHEMBL14411802 0.78 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL8751432 0.78 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL7899070 0.76 ESR1 (0.62) ESR1ESR2PDCD1CD274LMNA
SCHEMBL6747031 0.76 ESR1 (0.54) ESR1ESR2PDCD1CD274LMNA
SCHEMBL8580685 0.75 ESR1 (0.65) ESR1ESR2PDCD1CD274LMNA
SCHEMBL28501352 0.75 ESR1 (0.65) ESR1ESR2PDCD1CD274LMNA
SCHEMBL44658 0.75 ESR1 (1.00) ESR1ESR2PDCD1CD274LMNA
SCHEMBL7623734 0.75 TSHR (0.43) LMNACYP3A4ALOX15CYP2D6ADRA1A
SCHEMBL9561475 0.74 ESR1 (0.52) ESR1ESR2PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105693-A Polycarbonate resin composition and molded article thereof 住友化学株式会社 2020-12-18 CN disclosed
CN-105612195-B Ultraviolet-absorbing makrolon 株式会社ADEKA 2017-10-27 CN disclosed
EP-1970410-B1 AROMATIC POLYCARBONATE RESIN COMPOSITION FOR LIGHTGUIDE PLATE AND LIGHTGUIDE PLATE MITSUBISHI ENG PLASTICS CORP (JP) 2012-11-14 EP disclosed
EP-1970410-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION FOR LIGHTGUIDE PLATE AND LIGHTGUIDE PLATE Mitsubishi Engineering-Plastics Corporation (JP) 2008-09-17 EP disclosed