SCHEMBL459346

SCHEMBL459346

Oc1ccc2ccccc2c1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 3/20 0.60
▸ PTPN22 Q9Y2R2 1/20 0.60
▸ POLB P06746 1/20 0.56
▸ CYP1A2 P05177 3/20 0.54
▸ HSD17B10 Q99714 3/20 0.54
▸ USP2 O75604 1/20 0.54
▸ PAK1 Q13153 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ ALDH1A1 P00352 4/20 0.50
▸ ESR1 P03372 3/20 0.50
▸ ESR2 Q92731 3/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ GAA P10253 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ TSHR P16473 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.50
▸ ERN1 O75460 1/20 0.50
▸ IDO1 P14902 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29975482 1.00 CYP2A6 (0.60) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL29843641 0.83 PTPN22 (0.47) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL11138273 0.80 ESR1 (0.50) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL29362162 0.75 PTPN22 (0.65) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL29027 0.75 PTPN22 (0.65) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL29613822 0.75 PTPN22 (1.00) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL15400598 0.75 PTPN22 (0.65) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL449348 0.75 CYP2A6 (1.00) CYP2A6PTPN22CYP1A2HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL28347175 0.75 PTPN22 (1.00) CYP2A6PTPN22POLBCYP1A2HSD17B10
SCHEMBL28483 0.75 PTPN22 (1.00) CYP2A6PTPN22POLBCYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2025-01-30 — — US claimed
US-20240417568-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF THE BOEING COMPANY (US) 2024-12-19 — — US claimed
EP-4477720-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF The Boeing Company (US) 2024-12-18 — — EP claimed
EP-4413058-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES Evonik Operations GmbH (DE) 2024-08-14 — — EP claimed
CN-118055962-A Epoxy curing agent composition comprising naphthol and naphthol derivative 赢创运营有限公司 2024-05-17 — — CN claimed
WO-2023057234-A9 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2024-05-10 — — WO claimed
WO-2023057234-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2023-04-13 — — WO claimed
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 — — US claimed
JP-57152520-A — — None — — JP disclosed
CN-119638709-A Compound and method for producing the same 住友化学株式会社 2025-03-18 — — CN disclosed
CN-116751137-B Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination 华中师范大学 2025-03-07 — — CN disclosed
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2025-01-30 — — US disclosed
US-20240417568-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF THE BOEING COMPANY (US) 2024-12-19 — — US disclosed
EP-4477720-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF The Boeing Company (US) 2024-12-18 — — EP disclosed
US-3974084-A Process for the manufacture of anhydrous alkali metal arylate solutions and separation of the arylates from alkali metal sulfite HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-10 — — US disclosed
US-3960957-A 2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof SYNTEX CORPORATION (PM) 1976-06-01 — — US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 — — US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 — — US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 — — US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES SRM, PNMT, NIT2 CYP2A6 2620/4885PTPN22 4686/4885POLB 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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