Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288554 | 0.82 | ABL1 (0.47) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL4288550 | 0.82 | ABL1 (0.47) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL4288553 | 0.82 | ABL1 (0.47) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL11899645 | 0.82 | ABL1 (0.46) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL30721652 | 0.81 | LMNA (0.49) | LMNAPLA2G1BATG4B | |
| SCHEMBL8520282 | 0.78 | SLC29A1 (0.56) | LMNAALDH1A1PLA2G1BATG4BSLC29A1 | |
| SCHEMBL8520281 | 0.78 | SLC29A1 (0.56) | LMNAALDH1A1PLA2G1BATG4BSLC29A1 | |
| SCHEMBL4586534 | 0.76 | ABL1 (0.52) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL10211477 | 0.76 | ABL1 (0.53) | LMNAABL1RIN1ALBALDH1A1 | |
| SCHEMBL10211487 | 0.76 | ABL1 (0.46) | LMNAABL1RIN1ALBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569652-A4 | N SP 4 /SP-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | PHARMASSET INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1569652-A2 | N SP 4 /SP-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | Pharmasset Ltd. (BB) | 2005-09-07 | — | — | EP | disclosed |
| WO-2003063771-A3 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | PHARMASSET LTD (BB) | 2005-07-07 | — | — | WO | disclosed |
| WO-2003063771-A2 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | PHARMASSET LTD. (BB) | 2003-08-07 | — | — | WO | disclosed |