Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | PGK2 | P07205 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520281 | 1.00 | SLC29A1 (0.56) | SLC29A1LMNAMTORTHRBMDM2 | |
| SCHEMBL4623569 | 0.88 | LMNA (0.69) | SLC29A1LMNAHBBPMP22P2RY2 | |
| SCHEMBL4623566 | 0.88 | LMNA (0.69) | SLC29A1LMNAHBBPMP22P2RY2 | |
| SCHEMBL6760689 | 0.84 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL2442312 | 0.83 | LMNA (0.80) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL2442315 | 0.83 | LMNA (0.80) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20668770 | 0.82 | LMNA (0.53) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20668768 | 0.82 | LMNA (0.53) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL26320655 | 0.82 | LMNA (0.53) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL2802755 | 0.82 | LMNA (0.53) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053194-C | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 2000-06-07 | — | — | CN | disclosed |
| EP-0698611-B1 | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-20 | — | — | EP | disclosed |
| CN-1126726-A | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-17 | — | — | CN | disclosed |
| EP-0698611-A1 | Process for N-acyl-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-28 | — | — | EP | disclosed |