Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | PPARD | Q03181 | 11/20 | 0.37 |
| ▸ | PPARA | Q07869 | 11/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594609 | 0.93 | SSTR5 (0.38) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4594382 | 0.92 | SSTR5 (0.40) | SSTR5KCNH2 | |
| SCHEMBL4593246 | 0.91 | SSTR5 (0.41) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4593823 | 0.89 | SSTR5 (0.37) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4593907 | 0.89 | SSTR5 (0.37) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4594452 | 0.87 | SSTR5 (0.41) | SSTR5KCNH2 | |
| SCHEMBL4594820 | 0.87 | SSTR5 (0.39) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4594329 | 0.86 | SSTR5 (0.42) | SSTR5KCNH2 | |
| SCHEMBL4594594 | 0.86 | SSTR5 (0.35) | SSTR5KCNH2PPARGPPARDPPARA | |
| SCHEMBL4593310 | 0.85 | REN (0.41) | SSTR5KCNH2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | claimed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | claimed |
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |