Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828017 | 0.86 | ALDH1A1 (0.45) | CYP1A2LMNAALDH1A1MGLLPHGDH | |
| SCHEMBL4714632 | 0.86 | ALDH1A1 (0.45) | CYP1A2LMNAALDH1A1MGLLPHGDH | |
| SCHEMBL2258265 | 0.86 | ALDH1A1 (0.45) | CYP1A2LMNAALDH1A1MGLLPHGDH | |
| SCHEMBL2256323 | 0.86 | ALDH1A1 (0.45) | CYP1A2LMNAALDH1A1MGLLPHGDH | |
| SCHEMBL3437018 | 0.77 | ALDH1A1 (0.75) | CYP1A2TDP1LMNAALDH1A1HTT | |
| SCHEMBL21377151 | 0.75 | CYP1A2 (0.81) | CYP1A2TDP1LMNAALDH1A1HTT | |
| SCHEMBL24059119 | 0.74 | CYP1A2 (0.44) | CYP1A2TDP1LMNAALDH1A1MGLL | |
| SCHEMBL13779904 | 0.74 | CYP1A2 (0.56) | CYP1A2TDP1LMNAALDH1A1MGLL | |
| SCHEMBL6997610 | 0.74 | ALDH1A1 (0.70) | CYP1A2TDP1LMNAALDH1A1HTT | |
| N-Methylpiperidine SCHEMBL11878290 | 0.73 | LMNA (0.39) | CYP1A2TDP1LMNAMGLLPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904503-A1 | 1H-THIENO[2,3-C]-PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-04-02 | — | — | EP | claimed |
| WO-2007009898-A1 | 1H-THIENO[2,3-C]PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-01-25 | — | — | WO | claimed |
| EP-1904503-A1 | 1H-THIENO[2,3-C]-PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007009898-A1 | 1H-THIENO[2,3-C]PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-01-25 | — | — | WO | disclosed |