Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340059 | 0.84 | ALDH1A1 (0.38) | CHRM1ALDH1A1PIK3CDHRH3SMYD3 | |
| SCHEMBL20407545 | 0.80 | — | — | |
| SCHEMBL15566988 | 0.80 | CYP2D6 (0.40) | CHRM1HRH3SMYD3CHRM2ADRA2B | |
| SCHEMBL15567638 | 0.80 | CYP2D6 (0.40) | CHRM1HRH3SMYD3CHRM2ADRA2B | |
| SCHEMBL13683795 | 0.79 | PIK3CD (0.44) | ALDH1A1PIK3CDHRH3CYP2D6 | |
| SCHEMBL12123730 | 0.77 | CHRM1 (0.56) | CHRM1ALDH1A1PIK3CDHRH3SMYD3 | |
| SCHEMBL12229616 | 0.76 | CHRM3 (0.49) | CHRM1ALDH1A1PIK3CDHRH3SMYD3 | |
| SCHEMBL623089 | 0.75 | HRH3 (0.35) | PIK3CDHRH3KCNH2CACNA1I | |
| SCHEMBL13484776 | 0.75 | CHRM1 (0.55) | CHRM1ALDH1A1PIK3CDHRH3KCNH2 | |
| SCHEMBL624091 | 0.73 | MAOA (0.37) | ALDH1A1HRH3KCNH2CACNA1ILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |