Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798463 | 0.83 | RAB9A (0.50) | RAB9AHTTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL3803043 | 0.82 | PIP4K2C (0.46) | RAB9ALMNARXFP1NOD2EGFR | |
| SCHEMBL3795373 | 0.82 | EGFR (0.42) | RAB9ALMNARXFP1NOD2PIK3CD | |
| SCHEMBL3799478 | 0.81 | LMNA (0.45) | RAB9AHTTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL3803590 | 0.80 | LMNA (0.45) | RAB9AHTTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL3797069 | 0.80 | PIP4K2C (0.42) | RAB9AHTTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL3799186 | 0.80 | PIK3CD (0.41) | RAB9ALMNARXFP1NOD2PIK3CD | |
| SCHEMBL3805713 | 0.80 | PIK3CD (0.40) | RAB9AHTTLMNARXFP1NOD2 | |
| SCHEMBL3802291 | 0.80 | PIK3CD (0.41) | RAB9ALMNARXFP1NOD2PIK3CD | |
| SCHEMBL3799584 | 0.80 | PIP4K2C (0.41) | RAB9AHTTSMN1; SMN2LMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |