SCHEMBL4593915

SCHEMBL4593915

NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
F2 P00734 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40
CA2 P00918 15/20 0.37
CA1 P00915 14/20 0.37
LMNA P02545 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4523545 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL4425342 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL9617176 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL20561002 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL31261893 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL6740067 0.97 THRB (0.55) THRBF2PRSS1PRSS2PRSS3
SCHEMBL1554409 0.91 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
SCHEMBL27096212 0.91 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
Heptafluorobutyramide SCHEMBL809135 0.88 THRB (0.43) THRBF2PRSS1PRSS2PRSS3
SCHEMBL27096224 0.88 THRB (0.41) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678340-A4 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KESTER INC (US) 2008-07-23 EP claimed
EP-1678340-A2 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KAC Holdings, Inc. (US) 2006-07-12 EP claimed
WO-2005038070-A2 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KAC HOLDINGS, INC. (US) 2005-04-28 WO claimed
US-20050077502-A1 Surface reactive preservative for use with solder preforms KESTER, INC. 2005-04-14 US claimed
EP-1678340-A4 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KESTER INC (US) 2008-07-23 EP disclosed
EP-1678340-A2 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KAC Holdings, Inc. (US) 2006-07-12 EP disclosed
WO-2005038070-A2 SURFACE REACTIVE PRESERVATIVE FOR USE WITH SOLDER PREFORMS KAC HOLDINGS, INC. (US) 2005-04-28 WO disclosed
US-20050077502-A1 Surface reactive preservative for use with solder preforms KESTER, INC. 2005-04-14 US disclosed