SCHEMBL4523545

SCHEMBL4523545

NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
F2 P00734 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40
CA2 P00918 15/20 0.37
CA1 P00915 14/20 0.37
LMNA P02545 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4425342 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL9617176 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL20561002 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL31261893 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL4593915 1.00 THRB (0.59) THRBF2PRSS1PRSS2PRSS3
SCHEMBL6740067 0.97 THRB (0.55) THRBF2PRSS1PRSS2PRSS3
SCHEMBL1554409 0.91 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
SCHEMBL27096212 0.91 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
Heptafluorobutyramide SCHEMBL809135 0.88 THRB (0.43) THRBF2PRSS1PRSS2PRSS3
SCHEMBL27096224 0.88 THRB (0.41) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152554-A1 ORALLY ADMINISTRABLE COMPOSITIONS COMPRISING AVOCADO/SOYBEAN UNSAPONIFIABLES AND LIPOIC ACID AND METHODS OF ADMINISTRATION NUTRAMAX LABORATORIES, INC. (US) 2025-05-15 US claimed
US-12226397-B2 Orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid and methods of administration NUTRAMAX LABORATORIES, INC. (US) 2025-02-18 US claimed
CN-118813130-B Coating containing vermiform nano silicon dioxide particles and preparation process thereof 山东科翰硅源新材料有限公司 2024-12-10 CN claimed
CN-114561072-B Preparation method of inorganic filler doped modified FEP composite dielectric film 浙江工业大学 2023-07-25 CN claimed
CN-116338068-A Risk grading method for content of PFOS-containing solid waste toxic substances 沈阳沈化院测试技术有限公司 2023-06-27 CN claimed
US-20230063903-A1 METHOD OF SURFACE CHEMICAL FUNCTIONALIZATION FOR DEVELOPING OF FUNCTIONAL HYDROPHOBIC SURFACES CITY UNIVERSITY OF HONG KONG (HK) 2023-03-02 US claimed
CN-115491089-A Modified carbon nano tube-fluorocarbon resin and application thereof in wear-resistant aluminum veneer 山东海天七彩建材有限公司 2022-12-20 CN claimed
CN-114561072-A Preparation method of inorganic filler doped modified FEP composite dielectric film 浙江工业大学 2022-05-31 CN claimed
CN-108440817-B Hydrophobic and oleophobic polyolefin material and preparation method thereof 日丰企业集团有限公司 2021-03-02 CN claimed
CN-106751845-A A kind of electronic equipment thermal conductivity composite and preparation method thereof 郑州诚合信息技术有限公司 2017-05-31 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
US-3948654-A PERFLUORO-ORGANIC ACIDS OR ITS SALTS, AMIDES OR ESTERS XEROX CORPORATION (US) 1976-04-06 US claimed
JP-4025512-A None JP disclosed
US-20250386434-A9 FLUORORESIN LONG FILM, METAL-CLAD LAMINATE AND SUBSTRATE FOR CIRCUIT DAIKIN INDUSTRIES, LTD. (JP) 2025-12-18 US disclosed
EP-4600973-A1 DIELECTRIC AND METHOD OF MANUFACTURING SAME DAIKIN INDUSTRIES, LTD. (JP) 2025-08-13 EP disclosed
US-20250230289-A1 DIELECTRIC AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2025-07-17 US disclosed
US-4292402-A UNIFORM COATINGS FOR HYDROPHILIC COLLOID LAYERS; ANTISTATIC AGENTS AGFA-GEVAERT, N.V. (BE) 1981-09-29 US disclosed
US-4235959-A Photographic matt layers or surfaces HUYGHEBAERT PAUL ADMINISTRATOR (BE) 1980-11-25 US disclosed
EP-0015592-A1 Light-sensitive silver halide materials comprising fluorine-containing surfactants AGFA-GEVAERT N.V. (BE) 1980-09-17 EP disclosed
US-3948654-A PERFLUORO-ORGANIC ACIDS OR ITS SALTS, AMIDES OR ESTERS XEROX CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12226397-B2 Orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid and methods of administration ALOX15B, ALOX15, ALOX12 THRB 3515/4885F2 138/4885PRSS1 230/4885
US-20250152554-A1 ORALLY ADMINISTRABLE COMPOSITIONS COMPRISING AVOCADO/SOYBEAN UNSAPONIFIABLES AND LIPOIC ACID AND METHODS OF ADMINISTRATION ALOX15B, ALOX15, ALOX12 THRB 3515/4885F2 138/4885PRSS1 230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.