Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322435 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| SCHEMBL29954798 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| SCHEMBL8374276 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| SCHEMBL5702986 | 0.80 | ALDH1A1 (0.55) | ALDH1A1ALOX15KMT2ACNR1SMN1; SMN2 | |
| SCHEMBL3825118 | 0.80 | HDAC1 (0.51) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10411183 | 0.79 | ALDH1A1 (0.57) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| SCHEMBL6179341 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7259023 | 0.78 | HDAC1 (0.50) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 | |
| SCHEMBL19932503 | 0.78 | HDAC6 (0.58) | ALDH1A1HDAC6 | |
| SCHEMBL7027687 | 0.78 | CYP4F2 (0.50) | ALDH1A1ALOX15GAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898909-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1898914-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000435-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007000434-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |