Ethylene

Ethylene

SCHEMBL459401

C=C.C=CCOC(=O)C=C.O=C(O)CC(O)C(=O)OC(=O)C(O)CC(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
CASP1 P29466 6/20 0.36
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 4/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 3/20 0.35
HSD17B10 Q99714 1/20 0.35
THRB P10828 1/20 0.34
MAPK1 P28482 1/20 0.33
HPGD P15428 1/20 0.33
PKM P14618 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8003148 0.83 SMN1; SMN2 (0.40) CASP1SMN1; SMN2CYP3A4PKM
SCHEMBL1201601 0.83 SMN1; SMN2 (0.43) TSHRSMN1; SMN2ALDH1A1TP53HIF1A
SCHEMBL367991 0.81 SMN1; SMN2 (0.44) TSHRCASP1MAPTCACNA1BAPBA1
SCHEMBL7489183 0.81 SMN1; SMN2 (0.44) TSHRCASP1MAPTCACNA1BAPBA1
Ethylene SCHEMBL3909087 0.80 SMN1; SMN2 (0.52) MAPTSMN1; SMN2
Ethylene SCHEMBL459044 0.80 TSHR (0.38) TSHRCASP1SMN1; SMN2ALDH1A1THRB
SCHEMBL741143 0.80 SMN1; SMN2 (0.38) CASP1SMN1; SMN2
Allyl Alcohol SCHEMBL9630023 0.79 SMN1; SMN2 (0.43) TSHRCASP1SMN1; SMN2
Ethylene SCHEMBL5184263 0.78 TSHR (0.52) TSHRMAPTCACNA1BAPBA1SMN1; SMN2
Ethylene SCHEMBL461105 0.78 TSHR (0.52) TSHRMAPTCACNA1BAPBA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-10189752-B2 Moisture barrier coatings SURFACE CHEMISTS OF FLORIDA, INC. (US) 2019-01-29 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20180022661-A1 Moisture Barrier Coatings SURFACE CHEMISTS OF FLORIDA, INC. 2018-01-25 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed
WO-1998010928-A1 POLYETHYLENE OXIDE-CONTAINING POLYOLEFIN FILM DUPONT CANADA INC. (CA) 1998-03-19 WO disclosed