SCHEMBL741143

SCHEMBL741143

C=CCOC=C.O=C(O)CC(O)C(=O)OC(=O)C(O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
CASP1 P29466 3/20 0.35
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8003148 0.86 SMN1; SMN2 (0.40) SMN1; SMN2CASP1SLC22A6
Malic Acid SCHEMBL367943 0.86 SMN1; SMN2 (0.56) SMN1; SMN2CASP1SLC22A6
Allyl Alcohol SCHEMBL9630023 0.82 SMN1; SMN2 (0.43) SMN1; SMN2CASP1SLC22A6
SCHEMBL9644645 0.80 SMN1; SMN2 (0.41) SMN1; SMN2SLC22A6
Ethylene SCHEMBL459401 0.80 TSHR (0.37) SMN1; SMN2CASP1
SCHEMBL367991 0.80 SMN1; SMN2 (0.44) SMN1; SMN2CASP1SLC22A6
SCHEMBL7489183 0.80 SMN1; SMN2 (0.44) SMN1; SMN2CASP1SLC22A6
Ethylene SCHEMBL3909087 0.79 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6
SCHEMBL180343 0.79 SMN1; SMN2 (0.57) SMN1; SMN2SLC22A6
SCHEMBL9461207 0.78 TSHR (0.39) SMN1; SMN2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940873-B2 Crystalline anti-human IL-12 antibodies ABBVIE INC. (US) 2015-01-27 US claimed
US-8772458-B2 Crystalline anti-hTNFalpha antibodies ABBVIE BIOTECHNOLOGY LTD (BM) 2014-07-08 US claimed
US-8753839-B2 Compositions and methods for crystallizing antibodies ABBVIE INC. (US) 2014-06-17 US claimed
US-20140017256-A1 CRYSTALLINE ANTI-HUMAN IL-12 ANTIBODIES ABBVIE INC. (US) 2014-01-16 US claimed
EP-2684895-A1 Crystalline anti-hTNFalpha antibodies AbbVie Biotechnology Ltd (BM) 2014-01-15 EP claimed
US-20130309309-A1 CRYSTALLINE ANTI-HTNFALPHA ANTIBODIES ABBVIE BIOTECHNOLOGY LTD (BM) 2013-11-21 US claimed
US-8558048-B2 Stabilized protein crystals, formulations comprising them and methods of making them ALTHEA TECHNOLOGIES, INC. (US) 2013-10-15 US claimed
US-8436149-B2 Crystalline anti-hTNFalpha antibodies ABBVIE BIOTECHNOLOGY LTD (BM) 2013-05-07 US claimed
US-8404819-B2 Crystalline anti-human IL-12 antibodies ABBVIE INC. (US) 2013-03-26 US claimed
EP-2527364-A1 Crystalline anti-human IL-12 antibodies Abbott Laboratories (US) 2012-11-28 EP claimed
EP-0884994-A1 USES OF DENTURE ADHESIVE CONTAINING ALOE EXTRACT CARRINGTON LABORATORIES, INC. (US) 1998-12-23 EP claimed
US-5760102-A Uses of denture adhesive containing aloe extract CARRINGTON LABORATORIES, INC. (US) 1998-06-02 US claimed
US-5753723-A CROSSLINKED ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER, CHELATE COMPOUND CHANG TIANG SHING (US) 1998-05-19 US claimed
US-5736158-A MIXTURE OF PEROXY BLEACH CLEANER, FLUORIDE COMPOUND IN POLYMER MATRIX, SURFACTANT AND EFFERVERCENT AGENT THE BLOCK DRUG COMPANY (US) 1998-04-07 US claimed
WO-1997035555-A1 NEW PARTIAL DENTURE CLEANSER WITH FLUORIDE THE BLOCK DRUG COMPANY (US) 1997-10-02 WO claimed
WO-1997029731-A1 USES OF DENTURE ADHESIVE CONTAINING ALOE EXTRACT CARRINGTON LABORATORIES, INC. (US) 1997-08-21 WO claimed
EP-0625038-B1 DENTURE STABILIZING COMPOSITIONS PROCTER & GAMBLE (US) 1997-06-18 EP claimed
US-5543443-A DENTURE ADHESIVE CONTAINING HYDROPHILIC POWDER, ROOM TEMPERATURE VULCANIZABLE SILICONE LIQUID THAT CURES TO PEELABLE SOLID THE PROCTER & GAMBLE COMPANY (US) 1996-08-06 US claimed
EP-0625038-A1 DENTURE STABILIZING COMPOSITIONS. PROCTER & GAMBLE (US) 1994-11-23 EP claimed
WO-1993014737-A1 DENTURE STABILIZING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-08-05 WO claimed