SCHEMBL4594032

SCHEMBL4594032

COP(=O)(OOc1ccccc1)OOc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
PKM P14618 2/20 0.41
HTT P42858 1/20 0.41
SRC P12931 1/20 0.40
ACP3 P15309 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 1/20 0.38
LTA4H P09960 1/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28708046 0.96 CA4 (0.42) CA4PKMHTTSRCACP3
SCHEMBL9634847 0.86 L3MBTL1 (0.50) CA4PKMHTTSRCL3MBTL1
SCHEMBL28941447 0.80 SRC (0.52) HTTSRCL3MBTL1TDP1LMNA
SCHEMBL31332475 0.80 SRC (0.52) HTTSRCL3MBTL1TDP1LMNA
SCHEMBL16163141 0.78 SRC (0.40) CA4PKMHTTSRCL3MBTL1
SCHEMBL132822 0.77 SRC (0.54) CA4PKMHTTSRCL3MBTL1
SCHEMBL1725920 0.77 SRC (0.54) CA4PKMHTTSRCL3MBTL1
SCHEMBL28176982 0.76 L3MBTL1 (0.41) CA4PKMHTTSRCACP3
Triphenyl Phosphate SCHEMBL28089356 0.76 CYP3A4 (0.52) CA4PKMHTTSRCL3MBTL1
Ammonia Solution, Strong SCHEMBL11592405 0.76 SRC (0.52) CA4PKMHTTSRCL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818817-A Sugammadex sodium diphenyl phosphine oxide derivative impurity and preparation method thereof 常州亚邦制药有限公司 2020-02-21 CN disclosed
EP-1919977-A2 POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND METHODS OF MAKING SAME FRX Polymers, LLP (US) 2008-05-14 EP disclosed
WO-2007022008-A2 POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND METHODS OF MAKING SAME FRX POLYMERS, LLP (US) 2007-02-22 WO disclosed