SCHEMBL16163141

SCHEMBL16163141

O=P(OCl)(OCl)OOc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
KDM4E B2RXH2 1/20 0.35
LTA4H P09960 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 2/20 0.32
CA4 P22748 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634847 0.86 L3MBTL1 (0.50) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL11458252 0.82 ALDH1A1 (0.44) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL28941447 0.80 SRC (0.52) SRCL3MBTL1TDP1KDM4ETSHR
SCHEMBL31332475 0.80 SRC (0.52) SRCL3MBTL1TDP1KDM4ETSHR
SCHEMBL28708046 0.78 CA4 (0.42) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL4594032 0.78 CA4 (0.42) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL3065840 0.77 SRC (0.43) SRCL3MBTL1TDP1CYP2C9CYP2C19
SCHEMBL305506 0.77 SRC (0.54) SRCL3MBTL1TDP1KDM4ETSHR
SCHEMBL428879 0.77 SRC (0.54) SRCL3MBTL1TDP1KDM4ETSHR
SCHEMBL9856545 0.77 SRC (0.43) SRCL3MBTL1TDP1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118292297-B Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-11-15 CN claimed
CN-118292297-A Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-07-05 CN claimed
CN-118292297-B Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-11-15 CN disclosed
CN-118292297-B Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-11-15 CN disclosed
CN-118292297-A Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-07-05 CN disclosed
CN-118292297-A Washable flame retardant applied to filter material and application method thereof 东莞市三威新材料科技有限公司 2024-07-05 CN disclosed
EP-2984097-B1 HIGHLY ACTIVE NUCLEOSIDE DERIVATIVE FOR THE TREATMENT OF HCV ACHILLION PHARMACEUTICALS INC (US) 2017-03-29 EP disclosed
US-9447132-B2 Highly active nucleoside derivative for the treatment of HCV ACHILLION PHARMACEUTICALS, INC. (US) 2016-09-20 US disclosed
EP-2984098-A2 DEUTERATED NUCLEOSIDE PRODRUGS USEFUL FOR TREATING HCV Achillion Pharmaceuticals, Inc. (US) 2016-02-17 EP disclosed
EP-2984097-A1 HIGHLY ACTIVE NUCLEOSIDE DERIVATIVE FOR THE TREATMENT OF HCV Achillion Pharmaceuticals, Inc. (US) 2016-02-17 EP disclosed
WO-2016014527-A2 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT ACHILLION PHARMACEUTICALS, INC. (US) 2016-01-28 WO disclosed
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT ACHILLION PHARMACEUTICALS, INC. 2016-01-21 US disclosed
US-20140309164-A1 DEUTERATED NUCLEOSIDE PRODRUGS USEFUL FOR TREATING HCV ACHILLION PHARMACEUTICALS, INC. (US) 2014-10-16 US disclosed
US-20140309189-A1 HIGHLY ACTIVE NUCLEOSIDE DERIVATIVE FOR THE TREATMENT OF HCV ACHILLION PHARMACEUTICALS, INC. (US) 2014-10-16 US disclosed
WO-2014169280-A2 DEUTERATED NUCLEOSIDE PRODRUGS USEFUL FOR TREATING HCV ACHILLION PHARMACEUTICALS, INC. (US) 2014-10-16 WO disclosed
WO-2014169278-A1 HIGHLY ACTIVE NUCLEOSIDE DERIVATIVE FOR THE TREATMENT OF HCV ACHILLION PHARMACEUTICALS, INC. (US) 2014-10-16 WO disclosed
CN-101302327-B Halogen-free fire-resistant epoxy resin composition, film and copper clad laminate GUANGKE INDUSTRY CORP 2011-05-04 CN disclosed
CN-101302327-A Halogen-free fire-resistant epoxy resin composition, film and copper clad laminate GUANGKE INDUSTRY CORP (CN) 2008-11-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT NUDT1, DUT, ADAR SRC 3812/4885L3MBTL1 1370/4885TDP1 1464/4885
US-20140309189-A1 HIGHLY ACTIVE NUCLEOSIDE DERIVATIVE FOR THE TREATMENT OF HCV SLC28A1, SLC28A2, NUDT1 SRC 2283/4885L3MBTL1 3650/4885TDP1 1359/4885
US-20140309164-A1 DEUTERATED NUCLEOSIDE PRODRUGS USEFUL FOR TREATING HCV PNP, SLC29A1, SLC28A1 SRC 3411/4885L3MBTL1 1041/4885TDP1 896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.