SCHEMBL459425

SCHEMBL459425

CC(=O)CCC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27849781 0.83 ALDH1A1 (0.45)
SCHEMBL29067490 0.80
SCHEMBL10347895 0.79 PAOX (0.50)
SCHEMBL6831744 0.79 PAOX (0.50)
SCHEMBL1672373 0.76 ALDH1A1 (0.43)
SCHEMBL384244 0.75
SCHEMBL31016297 0.75 ALDH1A1 (0.56)
SCHEMBL6801343 0.73
SCHEMBL1868226 0.73
SCHEMBL12640188 0.73 ALDH1A1 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079698-A Process for preparing 1-chloro-1- (chloroacetyl) cyclopropane 北京旭阳科技有限公司 2020-12-15 CN disclosed
EP-2614068-A1 ANTHRA[2,3-B:7,6B']DITHIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2013-07-17 EP disclosed
US-20130161568-A1 Anthra[2,3-b:7,6-b']dithiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
CN-103154007-A Anthra[2,3-b:7,6b']dithiophene derivatives and their use as organic semiconductors MERCK PATENT GMBH 2013-06-12 CN disclosed
WO-2012031659-A1 ANTHRA[2,3-B:7,6B']DITHIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2012-03-15 WO disclosed
WO-1996007409-A1 ALKALOIDS AND THEIR ANTIVIRAL AGENTS KING'S COLLEGE LONDON (GB) 1996-03-14 WO disclosed
EP-0372816-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-29 EP disclosed
WO-1990006304-A1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-14 WO disclosed
EP-0372816-A1 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-13 EP disclosed
US-4229470-A Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity MONTEDISON S.P.A. (IT) 1980-10-21 US disclosed
US-4140794-A Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity MONTEDISON S.P.A. (IT) 1979-02-20 US disclosed
US-4064347-A Bis-basic ketones of fluorene and fluorenone RICHARDSON-MERRELL INC. (US) 1977-12-20 US disclosed
US-4041165-A TREATING DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1977-08-09 US disclosed
US-3937833-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-02-10 US disclosed