Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439535 | 1.00 | ANPEP (0.48) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL27814389 | 0.86 | ANPEP (0.46) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL15345385 | 0.81 | ANPEP (0.48) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL5680176 | 0.80 | ANPEP (0.37) | ANPEPALDH1A1KDM4EMEN1GAA | |
| SCHEMBL11214374 | 0.79 | ANPEP (0.46) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL20563530 | 0.77 | ANPEP (0.45) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL6910507 | 0.76 | ANPEP (0.44) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL860023 | 0.75 | EGFR (0.38) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL5684070 | 0.75 | ANPEP (0.46) | ANPEPALDH1A1KDM4ECA1CA2 | |
| SCHEMBL11355072 | 0.75 | ANPEP (0.43) | ANPEPCYP1A2CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524917-B1 | FUSED PYRIDINE DERIVATIVES | SIHUAN PHARMACEUTICAL HOLDINGS GROUP LTD (CN) | 2018-06-27 | — | — | EP | disclosed |
| CN-103848811-B | Uracil derivant, its preparation method and application thereof | 齐鲁制药有限公司 | 2016-12-21 | — | — | CN | disclosed |
| US-8680089-B2 | Fused pyridine derivatives | Xuanzhu Pharma Co., Ltd. (CN) | 2014-03-25 | — | — | US | disclosed |
| US-8680089-B2 | Fused pyridine derivatives | Xuanzhu Pharma Co., Ltd. (CN) | 2014-03-25 | — | — | US | disclosed |
| EP-2524917-A1 | FUSED PYRIDINE DERIVATIVES | Xuanzhu Pharmaco., Ltd. (CN) | 2012-11-21 | — | — | EP | disclosed |
| US-20120289497-A1 | FUSED PYRIDINE DERIVATIVES | Xuanzhu Pharma Co., Ltd. (CN) | 2012-11-15 | — | — | US | disclosed |
| US-20120289497-A1 | FUSED PYRIDINE DERIVATIVES | Xuanzhu Pharma Co., Ltd. (CN) | 2012-11-15 | — | — | US | disclosed |
| CN-102741251-A | Fused pyridine derivatives | SHANDONG XUANZHU MEDICINAL CO LTD | 2012-10-17 | — | — | CN | disclosed |
| EP-1931660-A2 | PHENYL-[1,2,4]-OXADIAZOL-5-ONE DERIVATIVES WITH PHENYL GROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007039178-A2 | PHENYL-[1,2,4]-OXADIAZOL-5-ONE DERIVATIVES WITH PHENYL GROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |
| EP-0351194-B1 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289497-A1 | FUSED PYRIDINE DERIVATIVES | GPR119, INSR, IAPP | ANPEP 3317/4885CYP1A2 395/4885CYP2C19 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.