Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | AKT1 | P31749 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3776916 | 0.99 | ALDH1A1 (0.65) | ALDH1A1HSD17B10AKT1LMNAGAB1 | |
| SCHEMBL3788763 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HSD17B10AKT1LMNAGAB1 | |
| Hydrochloric Acid SCHEMBL3776921 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HSD17B10AKT1LMNAGAB1 | |
| SCHEMBL3788760 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HSD17B10AKT1LMNAGAB1 | |
| Glyprothiazol SCHEMBL1814714 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HSD17B10AKT1LMNACA1 | |
| SCHEMBL5398574 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HSD17B10LMNACA1CA2 | |
| SCHEMBL5404610 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10LMNACA1KMT2A | |
| SCHEMBL5401314 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10LMNACA1CA2 | |
| SCHEMBL5388827 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10AKT1LMNACA1 | |
| SCHEMBL5395237 | 0.80 | ALDH1A1 (0.68) | ALDH1A1HSD17B10AKT1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937657-A1 | N-[1 ,3,4]-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039175-A1 | N-[1 ,3,4]-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |