SCHEMBL4594540

SCHEMBL4594540

O=C(O)C1CCC(CN2C(=O)C=CC2=O)CC1.O=C1CCC(=O)N1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.38
BACE2 Q9Y5Z0 1/20 0.38
LMNA P02545 2/20 0.38
PLG P00747 1/20 0.38
PLAT P00750 1/20 0.38
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
ANPEP P15144 1/20 0.35
ENPEP Q07075 1/20 0.35
CREBBP Q92793 1/20 0.33
KAT2A Q92830 1/20 0.33
KAT2B Q92831 1/20 0.33
CXCR3 P49682 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TACR1 P25103 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890390 0.89 LMNA (0.46) BACE1BACE2LMNAPLGPLAT
SCHEMBL159817 0.89 LMNA (0.46) BACE1BACE2LMNAPLGPLAT
Hydrochloric Acid SCHEMBL25415692 0.88 LMNA (0.44) BACE1BACE2LMNAPLGPLAT
SCHEMBL28102949 0.84 BACE1 (0.36) BACE1BACE2LMNAPLGPLAT
SCHEMBL28063070 0.84 BACE1 (0.36) BACE1BACE2LMNAPLGPLAT
Succinic Acid SCHEMBL23234379 0.84 PTGS1 (0.42) BACE1BACE2LMNAPLGPLAT
Succinimide SCHEMBL9845552 0.83 BACE1 (0.41) BACE1BACE2LMNAPLGPLAT
SCHEMBL16552327 0.81 PLG (0.47) BACE1BACE2LMNAPLGPLAT
SCHEMBL535579 0.81 PLG (0.47) BACE1BACE2LMNAPLGPLAT
SCHEMBL28880603 0.80 ANPEP (0.41) BACE1BACE2LMNAPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108226467-B Reversible cell labeling using conjugates with two releasable binding sites 美天施生物科技有限两合公司 2022-11-01 CN disclosed
CN-114616458-A Serial multi-channel microscopy 美天施生物科技有限两合公司 2022-06-10 CN disclosed
CN-113748217-A Systems, compositions, and methods for target entity detection 仁慈生物分析公司 2021-12-03 CN disclosed
CN-113677995-A Reversible cell detection using conjugates with linkers for increasing fluorescence brightness and enzymatically releasable fluorescent moieties 美天施生物科技有限两合公司 2021-11-19 CN disclosed
WO-2021101349-A1 ANTIBODY THAT BINDS TO ROR1 AND B7-H3, ANTIBODY-DRUG CONJUGATE CONTAINING SAME, AND USE THEREOF 에이비엘바이오 주식회사 2021-05-27 WO disclosed
CN-106170564-B Proximity assays based on detection of Hybrid Chain Reaction (HCR) 欧凌科生物科技公司 2020-01-03 CN disclosed
US-10031137-B2 Devices, methods, and kits for detecting an analyte in a sample DREXEL UNIVERSITY (US) 2018-07-24 US disclosed
US-20080213266-A1 Method for Treating CCR4-Related Diseases KYOWA HAKKO KOGYO CO., LTD. 2008-09-04 US disclosed
EP-1266032-B1 FUNCTIONALIZED ENCAPSULATED FLUORESCENT NANOCRYSTALS BIOCRYSTAL LTD (US) 2008-01-09 EP disclosed
US-5063109-A Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents ABBOTT LABORATORIES (US) 1991-11-05 US disclosed
US-5002883-A Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents ABBOTT LABORATORIES (US) 1991-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080213266-A1 Method for Treating CCR4-Related Diseases CCR4, CCR1, CCR6 BACE1 4415/4885BACE2 4765/4885LMNA 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.