Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159817 | 0.85 | LMNA (0.46) | BACE1BACE2PLGPLATLMNA | |
| SCHEMBL890390 | 0.85 | LMNA (0.46) | BACE1BACE2PLGPLATLMNA | |
| SCHEMBL4594540 | 0.84 | BACE1 (0.38) | BACE1BACE2PLGPLATLMNA | |
| Hydrochloric Acid SCHEMBL25415692 | 0.83 | LMNA (0.44) | BACE1BACE2PLGPLATLMNA | |
| SCHEMBL28102949 | 0.82 | BACE1 (0.36) | BACE1BACE2PLGPLATLMNA | |
| Succinic Acid SCHEMBL23234379 | 0.79 | PTGS1 (0.42) | BACE1BACE2PLGPLATLMNA | |
| Succinimide SCHEMBL9845552 | 0.79 | BACE1 (0.41) | BACE1BACE2PLGPLATLMNA | |
| SCHEMBL27444030 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28481361 | 0.78 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL535579 | 0.77 | PLG (0.47) | BACE1BACE2PLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103037900-B | Folate receptor 1 antibodies and immunoconjugates and uses thereof | IMMUNOGEN INC. (US) | 2016-04-06 | — | — | CN | disclosed |