SCHEMBL4594554

SCHEMBL4594554

CC(c1c(O)cccc1C(C)(C)C)c1c(O)cccc1C(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TDP1 Q9NUW8 3/20 0.56
TSHR P16473 3/20 0.56
CA2 P00918 6/20 0.52
GABRA1 P14867 3/20 0.45
GABRB2 P47870 3/20 0.45
ALOX15 P16050 4/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP1A2 P05177 2/20 0.39
ATP2A2 P16615 1/20 0.39
ATP2A3 Q93084 1/20 0.39
ALOX12 P18054 2/20 0.38
LMNA P02545 3/20 0.38
TYR P14679 2/20 0.38
HTT P42858 2/20 0.38
HSD17B10 Q99714 2/20 0.38
NR1I2 O75469 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958219 0.88 ALDH1A1 (0.56) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL11162580 0.87 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL27809376 0.77 CA2 (0.52) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL4596045 0.76 CYP2C9 (0.47) ALDH1A1TDP1TSHRCA2GABRA1
Isobutane SCHEMBL28034672 0.76 ALDH1A1 (0.86) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL2202117 0.73 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL8761536 0.73 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL30504750 0.73 CA2 (0.76) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL29888677 0.73 ALDH1A1 (0.65) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL7941421 0.73 CA2 (0.54) ALDH1A1TDP1TSHRCA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1437231-B1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API CORP (JP) 2008-01-09 EP disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed