⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487410 | 0.74 | — | — | |
| SCHEMBL3054786 | 0.74 | — | — | |
| SCHEMBL20311350 | 0.74 | — | — | |
| SCHEMBL457503 | 0.74 | — | — | |
| SCHEMBL7992683 | 0.74 | — | — | |
| SCHEMBL3712918 | 0.74 | — | — | |
| SCHEMBL740241 | 0.74 | — | — | |
| SCHEMBL304027 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1585973 | 0.72 | LOXL2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL22774344 | 0.72 | GRIN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690258-A | Nitrogenous heterocyclic-imide derivative and preparation method and purpose thereof | HUBEI BIOPESTICIDE ENGINEERING RES CT | 2012-09-26 | — | — | CN | claimed |
| US-12421240-B2 | Hydropyrazino[1,2-d][1,4]diazepine compounds for the treatment of autoimmune disease | HOFFMANN-LA ROCHE INC. (US) | 2025-09-23 | — | — | US | disclosed |
| CN-120192344-A | Bicyclocompounds, preparation method and medical application thereof | 上海济煜医药科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| US-20250179000-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2025-06-05 | — | — | US | disclosed |
| US-20250171459-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2025-05-29 | — | — | US | disclosed |
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| US-20250051347-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals, Inc. (CN) | 2025-02-13 | — | — | US | disclosed |
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-222342897-U | Nicosulfuron intermediate body acidification reaction device | 淄博新农基作物科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-222342897-U | Nicosulfuron intermediate body acidification reaction device | 淄博新农基作物科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| EP-0386565-B1 | Heterocyclic compounds | BAYER AGROCHEM KK (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0235725-B1 | HETEROCYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1991-11-21 | — | — | EP | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0386565-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4849432-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-18 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0235725-A2 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |