⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303902 | 0.79 | NPC1 (0.40) | — | |
| SCHEMBL12760430 | 0.75 | NFKB1 (0.46) | — | |
| SCHEMBL422266 | 0.74 | — | — | |
| SCHEMBL830410 | 0.74 | KDM4E (0.38) | — | |
| SCHEMBL459457 | 0.74 | — | — | |
| SCHEMBL11144847 | 0.74 | NOS3 (0.31) | — | |
| SCHEMBL2249764 | 0.74 | RARB (0.46) | — | |
| SCHEMBL14968355 | 0.74 | P2RX7 (0.37) | — | |
| SCHEMBL3712918 | 0.72 | — | — | |
| SCHEMBL487410 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 982 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499566-A | Pyridine derivative compound and preparation method thereof | 南京工业大学 | 2020-08-07 | — | — | CN | claimed |
| CN-122079899-A | Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein | — | 2026-05-26 | — | — | CN | disclosed |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2026-05-26 | — | — | US | disclosed |
| CN-118955455-B | Double-target piperine compound used as alpha-glucosidase inhibitor and aldose reductase inhibitor, and preparation method and application thereof | 湘潭大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2026-03-12 | — | — | US | disclosed |
| EP-4580620-A2 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS, COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | Hager Biosciences, LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |
| US-12275744-B2 | Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists | HAGER BIOSCIENCES, LLC (US) | 2025-04-15 | — | — | US | disclosed |
| US-12187738-B2 | Imidazolo derivatives, compositions and methods as orexin antagonists | HAGER BIOSCIENCES, LLC (US) | 2025-01-07 | — | — | US | disclosed |
| US-20020006932-A1 | Substituted heterocyclic siprodecane compound active as an antagonist of neurokinin 1 receptor | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-17 | — | — | US | disclosed |
| WO-2001094346-A1 | 1,3,8-TRIAZA-SPIRO'4,5&excl;DECAN-4-ONE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001092264-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1157021-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001062742-A1 | PIPERIDINE- AND PIPERAZINE SUBSTITUTED N-HYDROXYFORMAMIDES AS INHIBITORS OF METALLOPROTEINASES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |
| WO-2001036395-A1 | TRIAZOLES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001016121-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| WO-2000046221-A1 | SULFAMATO HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-10 | — | — | WO | disclosed |
| US-4871387-A | Pyri(mi)dyl-oxy-and -thio-benzoic acid derivatives useful as herbicides and plant growth regulants | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0226837-A2 | Pyri(mi)dyloxy and -thiobenzoic acid derivatives | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |