Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.79 |
| ▸ | TNKS | O95271 | 1/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.79 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.79 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL7122178 | 0.91 | HCAR2 (0.86) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL7122183 | 0.91 | HCAR2 (0.86) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL11809695 | 0.89 | HCAR2 (0.83) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL10881703 | 0.89 | HCAR2 (0.91) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL15169790 | 0.89 | HCAR2 (0.91) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1706935 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1332 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653828 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL50466 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL3406486 | 0.89 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113373466-A | Electrochemical synthesis method of beta-acetaminocarbonyl compound | 安徽科技学院 | 2021-09-10 | — | — | CN | disclosed |
| EP-1419815-B1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | TAKASAGO PERFUMERY CO LTD (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-7307037-B2 | Metallic catalysts for chemo-, regio- and stereoselective reactions, and corresponding precursors | CHEMI S.P.A. (IT) | 2007-12-11 | — | — | US | disclosed |
| EP-1761549-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| EP-1761548-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| US-7078568-B2 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-07-18 | — | — | US | disclosed |
| US-6987202-B2 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-01-17 | — | — | US | disclosed |
| WO-2006002730-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |
| WO-2006002729-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |
| US-20050288531-A1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | SHIMIZU HIDEO | 2005-12-29 | — | — | US | disclosed |
| US-5202493-A | CHIRAL TRIDENTATE BIS(PHOSPHOLANE) LIGANDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-13 | — | — | US | disclosed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5177230-A | Chiral phospholane transistor metal catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| US-5171892-A | Chiral phospholanes via chiral 1,4-diol cyclic sulfates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| US-5099077-A | Dihydrocarbylphosphioxy substituted groups with amine or phosphinoamines as ligands | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-03-24 | — | — | US | disclosed |
| US-5008457-A | Enantioselective hydrogenation of unsaturated compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
| US-4892971-A | Process for the preparation of n-acetylphenylalanine | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-09 | — | — | US | disclosed |
| US-4877908-A | Chiral phosphorus compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions | NORSOLOR (FR) | 1989-10-31 | — | — | US | disclosed |
| US-4187241-A | BIS(DIARYLPHOSPHINOMETHYL)CYCLOBUTANE, ENANTIOSELECTIVE HYDROGENATION CATALYSTS | HOFFMAN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4120870-A | Metal phosphine complex | HOFFMANN-LA ROCHE INC. (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288531-A1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | PHOSPHO1, PRMT1, PRMT9 | HCAR2 4579/4885HDAC3 3642/4885HDAC4 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.