SCHEMBL4594759

SCHEMBL4594759

C=CC(=O)OCC1=CCCCC1.CC1=C(C(=O)O)CC1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TAAR1 Q96RJ0 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.35
GSTP1 P09211 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301811 0.85 GSTP1 (0.40) ALDH1A1HSD17B10TAAR1SMN1; SMN2NPC1
Acrylic Acid SCHEMBL18169554 0.84 TAAR1 (0.43) ALDH1A1TAAR1SMN1; SMN2NPC1RAB9A
Acrylic Acid Methyl Ester SCHEMBL7196733 0.82 RAB9A (0.40) ALDH1A1MAPTHTTHSD17B10TAAR1
Methacrylic Acid SCHEMBL6379774 0.81 GSTP1 (0.36) ALDH1A1TAAR1L3MBTL1SMN1; SMN2NPC1
Acrylic Acid Methyl Ester SCHEMBL30093668 0.81 RAB9A (0.39) ALDH1A1MAPTHTTHSD17B10TAAR1
SCHEMBL19638926 0.77 HCAR2 (0.47) ALDH1A1L3MBTL1NPC1RAB9AMAPK1
SCHEMBL6379769 0.77 THRB (0.37) ALDH1A1HSD17B10TAAR1L3MBTL1SMN1; SMN2
SCHEMBL301941 0.76 NPC1 (0.34) ALDH1A1TAAR1SMN1; SMN2NPC1RAB9A
SCHEMBL38666286 0.75 TAAR1 (0.36) ALDH1A1HSD17B10TAAR1SMN1; SMN2NPC1
SCHEMBL85977 0.74 TSHR (0.46) ALDH1A1HSD17B10TAAR1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1878780-A1 Oxygen-scavenging compositions DSMIP Assets B.V. (NL) 2008-01-16 EP disclosed